Bioss Inc.'s SNRPA (2A1) Monoclonal Antibody is a Rabbit monoclonal antibody. The SNRPA (2A1) Monoclonal Antibody was generated using Snrpa as the antigen. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Precipitation, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunoprecipitation, and Western Blot.
Description
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs